Publications & Research

Functional MR Imaging May Help Detect Subtle Brain Connectivity Abnormalities in Patients with Mild Traumatic Brain Injury

Resting-state functional brain MR imaging demonstrates variations in default-mode network connectivity patterns in patients with mild traumatic brain injury (MTBI). In a study of 23 patients and 18 control subjects, Zhou and colleagues found significantly reduced connectivity in the posterior cingulate cortex and parietal regions and increased frontal connectivity around the medial prefrontal cortex in patients with MTBI.

Functional MR imaging may be a useful additional clinical tool with which to detect subtle brain injury that is unavailable with conventional MR imaging, and it may enable better understanding the postconcussion syndrome, the researchers concluded.

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