Publications & Research

Brain Volume Findings in 6-Month-Old Infants at High Familial Risk for Autism

In this study scientists used magnetic resonance imaging (MRI) to measure brain volume in 6-month-olds at high familial risk for autism.

Individuals with autism as young as 2 years have been observed to have larger brains than healthy comparison subjects. Studies using head circumference suggest that brain enlargement is a postnatal event that occurs around the latter part of the first year. To the authors’ knowledge, no previous brain imaging studies have systematically examined the period prior to age 2. The Infant Brain Imaging Study (IBIS) is a longitudinal imaging study of infants at high risk for autism. In this study they used magnetic resonance imaging (MRI) to measure brain volume in 6-month-olds at high familial risk for autism. This cross-sectional analysis compared brain volumes at 6 months of age in high-risk infants (N=98) and infants without family members with autism (N=36). MRI scans were also examined for radiologic abnormalities.

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