Follow-up protocol performs well in CT lung screening
Researchers reported good results with a protocol for working up patients with nodules found on CT lung screening, according to research in the February American Journal of Roentgenology. The algorithm produced low false-positive rates, and could make the establishment of large-scale CT screening programs more feasible.
Researchers in the International Early Lung Cancer Action Program (I-ELCAP) developed a follow-up protocol that uses shape, size, and growth rate for determining whether a lesion should be biopsied. They tested the algorithm in a study of almost 5,000 CT lung screening patients, finding that it yielded malignancies in almost three-fourths of fine-needle aspiration biopsies (FNABs), as well as 100% of bronchoscopies and one ultrasound-guided lymph nodule biopsy. Overall, less than 0.5% of CT-detected nodules were biopsied and found to be benign.
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