Contrast CT, PET/CT assess cancer therapy for melanoma

01.11.12
Publication: AuntMinnie By: Wayne Forrest

Dynamic contrast-enhanced CT and FDG-PET/CT can provide additional information to evaluate and confirm how well melanoma patients respond to immune-modulated and antiangiogenic cancer therapy, according to researchers from Dana-Farber Cancer Institute.

The group performed FDG-PET/CT and CT perfusion imaging scans in a phase I clinical trial of the use of bevacizumab plus ipilimumab to treat patients with unresectable stage III or IV melanoma. The researchers found that patients with FDG-PET/CT images showing partial metabolic response achieved longer disease-free survival than those with stable metabolic disease or progressive metabolic disease.

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